News & Announcements

Follow Professor Yi-Wei Chang on Linkedin   Woohoo — very excited to share our new paper published today in Nature Microbiology! “A conserved GTPase complex gates exocytosis for defence and parasitism across alveolates” In this study, we uncover a conserved molecular mechanism that controls regulated exocytosis across evolutionarily diverse alveolates: from rhoptry secretion during host-cell […]

Tabea C. Fricke, Ruth A. Pumroy, Julia A. Rocereta, José J. De Jesús-Pérez, George Oprita, Marvin J. A. Meyer, Christine Herzog, Frank G. Echtermeyer, Kerstin Hill, Andreas Leffler & Vera Y. Moiseenkova-Bell Nature Communications   Abstract Transient receptor potential vanilloid 2 (TRPV2) is a broadly expressed ion channel implicated in diverse physiological and pathological processes. […]

Now online: “Seeing the mechanisms of disease with cryoEM” on Penn Medicine—how near-atomic views of molecules help us decode what goes wrong in illness. #cryoEM #SciComm https://www.pennmedicine.org/news/seeing-the-mechanisms-of-disease-with-cryoem

Come and visit us on September 11. Table 25 with live presentation at 11:30AM. Check the schedule here.        

🔬 The 4th Structural Biology Symposium is almost here!Don’t miss out—there’s still time to register.Secure your spot by clicking the link below! https://isb.upenndev.pendari.com/4th-structural-biology-symposium/7871-2/

The Institute of Structural Biology (ISB) is announcing an annual Pilot Grant Program in the general area of Structural Biology. The goal of the ISB Pilot Grant Program is to facilitate collaborative research between groups that cross disciplines and draw on advances in Structural Biology techniques. The ISB Pilot Grant Program aims to increase appreciation […]

We are excited for Nick Palmer, Kyle Barrie, and the Dominguez Lab for this recent publication in Nature: Mechanisms of actin filament severing and elongation by formins. They  used cryo-EM to solve 7 structures of 2 formins, providing a step-by-step mechanism of actin severing and elongation. Read the full publication here: